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NEW STUDIES ADDEDTitle: Pulsed Electromagnetic Fields for Postsurgical Pain Management in Women Undergoing Cesarean Section
Location in PEMF Global Library: Pain Folder, Post-operative Recovery Folder Published: 2017 Applied Frequencies: 27.1 Hz Available in: Omnium1 2.0, iMRS Prime Abstract: To evaluate the efficacy of pulsed electromagnetic field (PEMF) in relation to reducing postoperative pain, analgesic use, and wound healing in patients undergoing Cesarean section (C-section). Conclusion: PEMF treatment after C-section decreases postsurgical pain, analgesic use, and surgical wound exudate and edema significantly, and is associated with a high level of patient satisfaction. NEW STUDIES ADDEDTitle: Epigenetic Modulation of Adult Hippocampal Neurogenesis by Extremely Low-Frequency Electromagnetic Fields Location in PEMF Global Library: Stem Cell Folder, Neurological Folder Published: 2014 Applied Frequencies: 1-100 HZ, with a focus on 50Hz Available in: iMRS Prime Trial Abstract: Throughout life, adult neurogenesis generates new neurons in the dentate gyrus of hippocampus that have a critical role in memory formation. Strategies able to stimulate this endogenous process have raised considerable interest because of their potential use to treat neurological disorders entailing cognitive impairment. We previously reported that mice exposed to extremely low-frequency electromagnetic fields (ELFEFs) showed increased hippocampal neurogenesis. Here, we demonstrate that the ELFEF dependent enhancement of hippocampal neurogenesis improves spatial learning and memory Conclusion: Our present study points to ELFEF stimulation as a good tool to enhance hippocampal neurogenesis and improve hippocampal-dependent memory functions in mice. The optimization of stimulation protocol and the characterization of ELFEF’s mechanisms at molecular levels in the animal model appear pivotal for translating results to humans. Our study identifies a novel molecular mechanism responsible for ELFEF-induced enhancement of hippocampal neurogenesis, which is of potential relevance for future stem cell-based therapeutic approaches. The discovery of the new CREB/NeuroD1 axis may be also relevant for treatment of brain disorders associated to alterations of these transcription factors. |
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