NEW STUDIES ADDEDTitle: Therapeutic potential of electromagnetic fields for tissue engineering and wound healing Location in PEMF Global Library: Published: 1 August 2014 Applied Frequencies: N/A Available in: N/A Abstract: Ability of electromagnetic fields (EMF) to stimulate cell proliferation and differentiation has attracted the attention of many laboratories specialized in regenerative medicine over the past number of decades. Recent studies have shed light on bio-effects induced by the EMF and how they might be harnessed to help control tissue regeneration and wound healing. Number of recent reports suggest that EMF has a positive impact at different stages of healing. Processes impacted by EMF include, but are not limited to, cell migration and proliferation, expression of growth factors, nitric oxide signalling, cytokine modulation, and more. Conclusion: Taking into account the great clinical potential of EMF, we can expect a rise in new techniques for tissue regeneration and wound healing in close perspective. Such strategy allows combining EMF with various chemical, physical and biological modalities to provide desired synergistic bio-effects and enhanced treatment efficacy. Title: Treatment of Delayed Union and Pseudarthrosis by Low Frequency Pulsing Electromagnetic Stimulation Location in PEMF Global Library: Published: September 1983 Applied Frequencies: 75Hz Available in: iMRS Prime Trial Abstract: The possibility of accelerating fractures healing by artificial means has always been an aspiration of the traumatologist, and from the end of the 18th century electrical stimulation has been used without, until recently, any success. The first important advance was by the researches of Japanese and American surgeons who showed that in a segment of bone subjected to a deforming load, positive electrical charges are induced along the convex (tension) side and negative charges along the concave (compression) side. Conclusion: Thirty-five cases of retarded union or established non-union were treated by low frequency pulsing electromagnetic stimulation. Consolidation was obtained in 31 cases (88.5 %) in an average period of 6 months. There were failures, the reasons for which are analysed. The history, development, and present technique of electromagnetic therapy are described. Our results show that it is an effective method of treatment in cases with or without infection, in cases in which previous bone grafts have failed, and in cases with associated soft tissue lesions. A fundamental requisite of treatment is that the fracture should be efficiently immobilised. The duration of the pseudarthrosis, its site and pathological characteristics do not appear to have significant effect on the outcome of treatment. We did not observe any significant side effects. In the opinion of the authors, this method of treatment may have application in wider fields, particularly in. the treatment of fresh fractures. Title: Time-Varying and Static Magnetic Fields in Therapeutic Applications: From Mechanisms to Clinical Results Location in PEMF Global Library: Published: October 2000 Applied Frequencies: N/A Available in: N/A Abstract: Time-varying electromagnetic fields (PMF) and static magnetic fields (10-4000 Gauss) have produced physiologically meaningful bioeffects despite their vastly different physical properties. This study considers the biophysical characteristics of each signal and compares the cellular and clinical results to those expected from predictions of dosimetry calculations. Conclusion: The analyses presented in this study strongly suggest that, if ion/ligand binding with known kinetics is the EMF-sensitive target, any pulsing or static magnetic field may be predictively configured to achieve the correct dosimetry for a physiologically meaningful bioeffect. This may provide part of the basis of a unified theory for weak EMF bioeffects. Title: Utilizing Pulsed Electromagnetic Field (PEMF) Therapy (Diapulse®) for Drug-Free Pain Management to Eliminate Reliance on Opioids for Non-Malignant Chronic Pain: A literature Review and Proposal for Pilot Study
Location in PEMF Global Library: Published: 17 June 2019 Applied Frequencies: 27.7 MHz (975 Watts per pulse) and pulse frequency set at 600 cps Available in: iMRS Prime Trial Abstract: The Federal and State governments have declared the presence of an opioid addiction pan-demic in the United States claiming the lives of more than 55,000 in 2015 (Rudd RA, Seth P, David F and Scholl L. 2016). The pharmaceutical manufacturers of the numerous FDA-approved opioid drugs are raking in more than $5 billion per year with about 2 million chronic pain sufferers addicted. The irony of this narcotic use and abuse conundrum is the existence of evidence-based technology for drug-free pain management which is not covered for reimbursement among public and private third-party payers. Therefore, this paper is presented to propose a pilot study to demonstrate the efficacy of resolving the chronic inflammation, edema and ischemia that causes non-malignant chronic pain with PEMF therapy, a non-invasive, non-thermal radio transmission of electrical impulses, thereby invalidating the legitimacy of prescribing opioid analgesics in such cases. Conclusion: There are no solutions being offered to replace opioid consumption with a non-pharmacological non-invasive anti-inflammatory modality such as PEMF therapy. Pain management as a medical specialty has been a massive failure because the most common method of treatment is long term opioid consumption. The popular trend declaring pain to be a disease rather than a symptom since the 1990s has led to the large-scale masking of pain-causing chronic inflammation, leaving the underlying condition mainly untreated. Moreover, the universal side effect of opioids, called “tolerance,” requires larger and larger doses to achieve the same effect leaving patients at risk of dying from opioid-related complications.
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