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Scientific Sunday Series

6/19/2022

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Traumatic Brain Injury & Concussion...


Title: Attenuation of interleukin-1beta by pulsed electromagnetic fields after traumatic brain injury

Location in PEMF Global Library: Traumatic Brain Injury & Concussion Folder
Published: 2012
​
Applied Frequencies: 2 Hz
Available in: Omnium1, iMRS Prime Trial
 
Abstract: This study explored whether PEMF signals could alter the course of IL-1β Production in rats subjected to closed-head contusive weight-drop injuries (Marmarou method) and penetrating needle-stick brain injuries.
 
Conclusion: Results demonstrate that PEMF treatment attenuated IL-1β levels up to 10-fold in CSF within 6 h after contusive injury and also significantly suppressed IL-1β within 17–24 h after penetrating injury. In contrast, no differences in IL-1β were seen between PEMF-treated and control groups in brain homogenates.

Title: Increases in microvascular perfusion and tissue oxygenation via pulsed electromagnetic fields in the healthy rat brain

Location in PEMF Global Library: Traumatic Brain Injury & Concussion Folder
Published: October 2014
​
Applied Frequencies: 5 Hz
Available in: Omnium1, iMRS Prime Trial
 
Abstract: The authors hypothesized that in the brain, PEMF increase nitric oxide (NO), which induces vasodilation, enhances microvascular perfusion and tissue oxygenation, and may be a useful adjunct therapy in stroke and traumatic brain injury. To test this hypothesis, they studied the effect of PEMF on a healthy rat brain with and without NO synthase (NOS) inhibition.
 
Conclusion: Thirty minutes of PEMF treatment induced cerebral arteriolar dilation leading to an increase in microvascular blood flow and tissue oxygenation that persisted for at least 3 hours. The effects of PEMF were mediated by NO, as we have shown in NOS inhibition experiments. These results suggest that PEMF may be an effective treatment for patients after traumatic or ischemic brain injury.

Title: Repetitive Transcranial Magnetic Stimulation Promotes Neural Stem Cell Proliferation and Differentiation after Intracerebral Hemorrhage in Mice

Location in PEMF Global Library: Traumatic Brain Injury & Concussion Folder
Published: February 2019
​
Applied Frequencies: 10 Hz
Available in: iMRS Prime Trial
 
Abstract: With in vivo and in vitro assays, the present study sought to investigate how repetitive transcranial magnetic stimulation (rTMS) influences neural stem cells (NSCs) after intracerebral hemorrhage (ICH) and the possible mechanism.
 
Conclusion: We found that rTMS significantly reduced brain edema and alleviated neural functional deficits. The mice that underwent ICH recovered faster after rTMS treatment, with apparent proliferation and neuronal differentiation of NSCs and attenuation of glial differentiation and GFAP aggregation.

Title: Cerebral use of a pulsating magnetic field in neuropsychiatry patients with long-term headache

Location in PEMF Global Library: Traumatic Brain Injury & Concussion Folder
Published: December 1985

Applied Frequencies: 260 Hz
Available in: iMRS Prime Trial
 
Abstract: A pulsed magnetic field (f = 260 Hz; t = 3 ms; induction B = 1.9 mT; gradient = 0.5 mT/cm) was applied at 40 patients with headaches of various etiology. The change of cephalea intensity was evaluated according to the patients’ statements.
 
Conclusion: The retreat of subjective difficulties as well as the amelioration of EEG were stated accordingly at headaches, which were bounded with cerebral arteriosclerosis, with states after cerebral concussion, with depressive neurosis, or with tension headache. Pulsed magnetic field could be applied only there, where the visual evaluation stated EEG as physiological.

f you are interested in reading any of these studies in their entirety, please contact us stating the studies you are interested in.
 
For further questions about the PEMF Global Library please email info@pemfglobal.com

Want complete access to the library?  

Simply purchase an Omnium1 2.0 or iMRS through PEMF Global. Call 
1-833-879-7363 for more information.
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