SCIENTIFIC SUNDAY SERIES

NEW STUDIES ADDED

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.Title:  Early application of pulsed electromagnetic field in the treatment of postoperative delayed union of long-bone fractures: a prospective randomized controlled study

Location in PEMF Global Library: Bone Density, Fractures, Breaks Folder
Published: 2013
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Applied Frequencies: Not listed
Available in: NA
 
Abstract: Pulsed electromagnetic field (PEMF) is reported to be an effective adjunct for the management of non-union long-bone fractures. Most studies implement PEMF treatment after 6 months or longer of delayed union or non-union following fracture treatment. Despite these variations in treatment, the early application of PEMF following a diagnosis of a postoperative delayed union has not been specifically analyzed. In this study, the outcomes of postoperative delayed union of long-bone fractures treated with an early application of PEMF were evaluated as compared with a sham-treated control group.
 
Conclusion: Fracture patients treated with an early application of PEMF achieved a significantly increased rate of union and an overall reduced suffering time compared with patients that receive PEMF after the 6 months or more of delayed union, as described by others.

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Title: Pulsed Electromagnetic Field (PEMF): Effective Adjuvant Therapy in Venous and Vasculitis Leg Ulcers

Location in PEMF Global Library: Circulation, Diabetes Folder
Published: 2008

Applied Frequencies: 4Hz, 75Hz
Available in: Omnium1 2.0, iMRS Prime Trial
 
Abstract: Chronic leg ulcers occur in 1% of the adult population with considerable associated morbidity and tend to follow a chronic course of recurrent healing and breakdown. Venous insufficiency is the commonest cause of chronic leg ulcers in the community, but vasculitis ulcers are known to be more resistant to treatment and more painful than ulcers of other aetiologies. A proportion of leg ulcers will heal on conservative treatment, those which do not respond cause considerable distress. Many modalities have been used for conservative treatment of leg ulcers and pulsed electromagnetic field (PEMF) was used for wound healing as it has several well documented physiological effects on cells and tissues. 
Conclusion: PEMF therapy improve the rate and degree of healing and reduces pain in resistant venous and vasculitis leg ulcers, this suggests that it could be a useful addition as an effective adjuvant treatment to non surgical therapy of leg ulcers. There is need for further studies in a larger population to determine the optimal treatment dose, timing and duration of electromagnetic therapy and applicability of using it in resistant ulcers of other aetiologies.

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Title: Therapeutic potential of electromagnetic fields for tissue engineering and wound healing 

Location in PEMF Global Library: Tissue Regeneration, Wound Healing Folder
Published: 2014

Applied Frequencies: Emphasis on 3-30Hz
Available in: Omnium1 2.0, iMRS Prime
 
Abstract:  Ability of electromagnetic fields (EMF) to stimulate cell proliferation and differentiation has attracted the attention of many laboratories specialized in regenerative medicine over the past number of decades. Recent studies have shed light on bio effects induced by the EMF and how they might be harnessed to help control tissue regeneration and wound healing. Number of recent reports suggests that EMF has a positive impact at different stages of healing. Processes impacted by EMF include, but are not limited to, cell migration and proliferation, expression of growth factors, nitric oxide signalling, cytokine modulation, and more. These effects have been detected even during application of low frequencies (range: 30–300 kHz) and extremely low frequencies (range: 3–30 Hz). In this regard, special emphasis of this review is the applications of extremely low-frequency EMFs 3-30 Hz, due to their biosafety and therapeutic efficacy
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Conclusion: Employment of EMF in regenerative medicine opens a new avenue for treatment of various diseases. Due to its non-ionizing and non-invasive nature, the use of EMF has evident advantages compared to current chemical, biological and physical methods of tissue regeneration and wound healing. Electric and magnetic components of EMF could be employed separately or in combination for different therapeutic purposes. Both components have demonstrated a capability for stimulating cell proliferation and differentiation. Considering the great clinical potential of EMF, we can expect a rise in new techniques for tissue regeneration and wound healing in close perspective. Such strategy allows combining EMF with various chemical, physical and biological modalities to provide desired synergistic bio-effects and enhanced treatment efficacy

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Title:  Variable spatial magnetic field influences peripheral nerves regeneration in rats

Location in PEMF Global Library: Nerve and Neuropathy, Tissue Regeneration Folder
Published: 2013

Applied Frequencies: 2-120 Hz – Special Emphasis on 40Hz
Available in: iMRS Prime Trial
 
Abstract: Generator of spatial magnetic field is one of most recent achievements among the magnetic stimulators. This apparatus allows to obtain the rotating magnetic field. This new method may be more effective than other widely used techniques of magnetic stimulation and magnetotherapy. We investigated the influence of alternating, spatial magnetic field on the regeneration of the crushed rat sciatic nerves. The experimental groups (A, B, C) were exposed (20 min/day, 5 d/week, 4 weeks) to alternating spatial magnetic field of three different intensities. Sciatic Functional Index (SFI) and tensometric assessments were performed every week after nerve crush. 
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Conclusion: Results obtained in this experiment show clearly that spatial alternating magnetic field has beneficial influence on peripheral nerve regeneration after injury.